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KMID : 0604520070330030175
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Journal of the Society of Cosmetic Scientists of Korea
2007 Volume.33 No. 3 p.175 ~ p.179
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The Study on Anti-obesity Activity of the Wild Plants of Jeju Island
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Jung Eun-Sun
Lee Jong-Sung
Jung Kwang-Seon
Kim Sae-Bom
Hur Sung-Ran
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Abstract
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In this study, we investigated the anti-obesity activity of extracts collected from wild plants in Jeju island. The inhibitory effect of plant extracts on the differentiation of preadipocyte 3T3-L1 was examined by oil red-O staining. We found that extracts collected from 6 plants among 31 plants, namely, Aralia elata(Miq.) Seem, Polygonum multiflorum Thunberg, Artemisia asiatica, platycodon grandiflorum(Jacq.) A. Dc., Polygonum cuspidatum S. et Z., Magnolia obovata Thunb, significantly inhibited preadipocyte differentiation. Additionally, 4 plant extracts were also found to have antioxidant activities in DPPH radical scavenging assay. Taken together, these results show that 6 plant extracts suppress the differentiation of preadipocytes, suggesting the potential use of 6 plant extracts as anti-obesity agents.
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KEYWORD
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anti-obesity, preadipocyte, differentiation, DPPH radical scavenging assay, oil red-O staining method
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